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................................ EnCapsulation Technology ................................

Agriculture ......... Animal Feed ......... Enzymes .......... Milling ............ Pharmaceutical .......... Proteins ........... Vaccines

EnCapsulation Technology.

We have discovered a new method for making valuable proteins. This involves protein-starch encapsulation technology. We have named this EnCapsulation™, a process by which valuable proteins are encapsulated inside starch granules for commercial use. Our proprietary technologies bring together advances in molecular biology and classical techniques for isolating proteins and utilising starches from plants. Our principal objective is to maximize the value of our EnCapsulation™ technologies through the development of multiple products in a broad range of industries including agriculture, chemicals, milling, industrial enzymes, vaccines, animal feed and protein pharmaceuticals. EnCapsulation™ technology uses a process that untilizes the natural process of starch biosynthesis in plants.


EnCapsulation™ technology can be used to encapsulate any and all proteins which are coded for by single genes. Unlike other approaches that create recombinant proteins, EnCapsulation™ technologies produces high-quality high-purity proteins that can be readily and easily harvested from plants. Such pure-protein technology has a wide range of applications in agriculture, animal feed, therapeutics, vaccines, milling, enzymes. EnCapsulation™ technology can also be used to make a protein which is slowly released during animal digestion. Such slow-release ExScaliber™ technology has applications in animal feed and human therapeutics.

First, identify your valuable protein and isolate the gene encoding such protein.

Second, the individual genes are engineered to contain a starch-locator fragment which is then together placed in the genome of a plant that makes starch (such as miaze, rice, potato and other starch storing plants).



Third these plants are grown and the starch-storing organs (seed or tubers) which will now be carrying the new protein with its starch-locator fragment.



Fourth the seed or tubers are harvested and can be stored.

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Fifth the starch granules may be extracted and purified. The starch can then be sold directly as animal feed.

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Sixth the protein-encapsulated in the starch may be released from the starch and purified using a variety of methods.



Seventh the protein may be released from its starch-locator fragment if required.



© 2000 ExSeed Genetics L.L.C.